Table 2.
Comparison of patients with and without AoE
| No AoE (n = 56) | AoE (n = 112) | P-value | |
|---|---|---|---|
| Clinical characteristics | |||
| Patients with MFS, n (%) | 37 (66) | 66 (59) | 0.37 |
| Age at first examination (years) | 16 ± 17 | 29 ± 16 | <0.001 |
| Male sex, n (%) | 18 (32) | 72 (64) | <0.001 |
| Family members, n (%) | 37 (66) | 53 (47) | 0.02 |
| Echocardiographic parameters | |||
| Age at echocardiography (years) | 23 ± 16 | 38 ± 15 | <0.001 |
| MAD, n (%) | 24 (43) | 45 (40) | 0.74 |
| Posterolateral MAD distance (mm) | 7 ± 3 | 8 ± 3 | 0.10 |
| Posterolateral MAD distance indexed (mm/m2) | 5.1 ± 2.3 | 4.3 ± 1.2 | 0.07 |
| Anterolateral MAD distance (mm) | 6 ± 2 | 7 ± 3 | 0.12 |
| Anterolateral MAD distance indexed (mm/m2) | 4.5 ± 2.9 | 3.6 ± 1.5 | 0.16 |
| MVP, n (%) | 15 (27) | 37 (33) | 0.41 |
| Mitral regurgitation, n (%) | 4 (7) | 26 (23) | 0.01 |
| Diastolic mitral annulus diameter indexed (mm/m2) | 19 ± 7 | 17 ± 3 | 0.01 |
| Systolic mitral annulus diameter indexed (mm/m2) | 18 ± 7 | 16 ± 3 | 0.01 |
| Dilated mitral annulus (n = 136, adult patients only), n (%) | 5 (9) | 41 (37) | 0.006 |
Values are average ± SD or frequencies (%). P-values are calculated by Student’s t test or chi-square as appropriate. Bold values denote statistical significance.
AoE, aortic events; MAD, mitral annulus disjunction; MFS, Marfan syndrome; MVP, mitral valve prolapse.