Table 3.
Conventional Computed Tomography (CT) Imaging Characteristics Before Treatment
| Characteristics | Primary T790M (n = 103) | Acquired T790M (n = 103) | P-value |
|---|---|---|---|
| Multiple primary lung cancers | 36 (34.95) | 11 (10.68) | <0.001 |
| Location | 0.082 | ||
| Central | 8 (7.77) | 16 (15.53) | |
| Peripheral | 95 (92.23) | 87 (84.47) | |
| Long-axis diameter (cm) | 2.30 (1.62, 2.98) | 3.30 (2.50, 4.18) | <0.001 |
| Short-axis diameter (cm) | 1.80 (1.30, 2.20) | 2.50 (1.82, 3.30) | <0.001 |
| Presence of GGO | 54 (52.43) | 23 (22.33) | <0.001 |
| Spiculated sign | 63 (61.17) | 59 (57.28) | 0.571 |
| Air bronchogram | 60 (58.25) | 28 (27.18) | <0.001 |
| Vacuole sign | 23 (22.33) | 11 (10.68) | 0.024 |
| Lobulation sign | 90 (87.38) | 88 (85.44) | 0.684 |
| Vessel convergencea | 15 (15.79) | 18 (20.69) | 0.391 |
| Pleura attachmenta | 37 (38.95) | 49 (56.32) | 0.019 |
| Pleural indentationa | 39 (41.05) | 34 (39.08) | 0.786 |
| Pleural effusion | 4 (3.88) | 20 (19.42) | 0.001 |
Notes: Data are numbers of patients, with percentages in parentheses or medians; interquartile ranges are in parentheses. aThese CT characteristics were evaluated when the tumor was located peripherally.
Abbreviation: GGO, ground-glass opacity.