Table 2. Positive percent agreement, including 95% confidence intervals, for all assays with reference to both nasopharyngeal and anterior nares PCR.
Assay | NP Swab PCR | AN Swab PCR | ||
---|---|---|---|---|
Sensitivity < = 1000 copies/μL (95% CI) | Sensitivity >1000 copies/μL (95% CI) | Sensitivity < = 1000 copies/μL (95% CI) | Sensitivity >1000 copies/μL (95% CI) | |
OA-LFA | 25% (12%-42%), 9/36 | 92% (83%-97%), 66/72 | 55% (36%-73%), 17/31 | 98% (91%-100%), 58/59 |
Sofia® | 38% (22%-55%), 14/37 | 92% (83%-97%), 67/73 | 64% (45%-80%), 21/33 | 98% (91%-100%), 58/59 |
BinaxNOW™ | 53% (35%-70%), 19/36 | 96% (88%-99%), 70/73 | 79% (61%-91%), 26/33 | 98% (91%-100%), 58/59 |
MSD Ag ELISA | 46% (29%-63%), 17/37 | 96% (88%-99%), 70/73 | 76% (58%-89%), 25/33 | 100% (94%-100%), 59/59 |
AN Swab PCR | 57% (39%-73%), 21/37 | 97% (90%-100%), 71/73 | NA | NA |
Results are binned into two groups based on if the reference method measured less than or equal or above 1000 copies per microliter.