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. 2021 Aug 17;16(8):e0252781. doi: 10.1371/journal.pone.0252781

Table 4. Characteristics of neuropathic pain only in NCP patients in the presence or absence of the clinical predictors of NCP.

Total Age (years) (N = 722) Cancer duration (months) (N = 722) Cancer stage (N = 657) Chemotherapy (N = 722) Pain VAS (N = 722)
<65 (N = 489) ≥65 (N = 233) P-value ≥6 (N = 579) <6 (N = 143) P-value I–III (N = 163) IV (N = 494) P-value Yes (N = 668) No (N = 54) P-value ≥4 (N = 497) <4 (N = 225) P-value
Burning 128 (64.6) 70 (35.4) 0.317 156 (78.8) 42 (21.2) 0.633 41 (22.3) 143 (77.7) 0.404 180 (90.9) 18 (9.1) 0.393 146 (73.7) 52 (26.3) 0.097
Painful cold 229 (66.4) 116 (33.6) 0.507 272 (78.8) 73 (21.2) 0.436 74 (23.7) 238 (76.3) 0.599 318 (92.2) 27 (7.8) 0.844 266 (77.1) 79 (22.9) <0.001
Electric shocks 420 (66.5) 212 (33.5) 0.069 510 (80.7) 122 (19.3) 0.450 143 (25.0) 430 (75.0) 0.927 587 (92.9) 45 (7.1) 0.449 439 (69.5) 193 (30.5) 0.401
Tingling 437 (68.5) 201 (31.5) 0.276 520 (81.5) 118 (18.5) 0.022 146 (25.0) 438 (75.0) 0.861 591 (92.6) 47 (7.4) 0.924 439 (68.8) 199 (31.2) 1.000
Pins and needles 314 (66.7) 157 (33.3) 0.452 373 (79.2) 98 (20.8) 0.409 108 (24.9) 325 (75.1) 0.989 432 (91.7) 39 (8.3) 0.331 345 (73.2) 126 (26.8) 0.001
Numbness 271 (68.1) 127 (31.9) 0.88 331 (83.2) 67 (16.8) 0.033 95 (26.2) 268 (73.8) 0.420 367 (92.2) 31 (7.8) 0.835 275 (69.1) 123 (30.9) 0.932
Itching 154 (70.0) 66 (30.0) 0.437 176 (80.0) 44 (20.0) 1.000 55 (26.6) 152 (73.4) 0.541 206 (93.6) 14 (6.4) 0.548 147 (66.8) 73 (33.2) 0.492
Touch hypoesthesia 299 (68.6) 137 (31.4) 0.602 362 (83.0) 74 (17.0) 0.024 102 (25.6) 296 (74.4) 0.610 409 (93.8) 27 (6.2) 0.139 291 (66.7) 145 (33.3) 0.156
Prick hypoesthesia 136 (68.0) 64 (32.0) 0.994 166 (83.0) 34 (17.0) 0.286 52 (28.0) 134 (72.0) 0.283 187 (93.5) 13 (6.5) 0.645 138 (69.0) 62 (31.0) 1.000
Hyperesthesia 141 (74.6) 48 (25.4) 0.024 155 (82.0) 34 (18.0) 0.533 37 (22.3) 129 (77.7) 0.444 173 (91.5) 16 (8.5) 0.661 135 (71.4) 54 (28.6) 0.421

χ2 test

Multiple-choice response.

NCP: Neuropathic cancer pain; VAS: Visual analog scale.