Table 2.

Association of serum VEGF and IGF-1 levels with patients’ characteristics

	VEGF, pg/ml		IGF-1, ng/ml
	median ± SD	p	median ± SD	p
Age
<60 years	459.0 ± 362.8	0.198	36.6 ± 30.2	0.893
≥60 years	510.7 ± 272.7		39.2 ± 32.1
Gender
Male	461.8 ± 313.1	0.572	37.6 ± 30.9	0.894
Female	521.0 ± 358.1		37.9 ± 31.5
Previous operation
+	429.2 ± 281.3	0.010	34.9 ± 28.4	0.174
−	601.1 ± 395.6		44.2 ± 35.8
Lauren’s classification
Diffuse	369.1 ± 215.2	0.030	31.0 ± 29.9	0.520
Intestinal	435.3 ± 224.2		28.7 ± 27.8
Mixed	519.4 ± 426.0		36.5 ± 25.8
Unknown	546.8 ± 364.1		44.9 ± 33.0
Adjuvant chemotherapy
+	450.4 ± 308.0	0.177	28.7 ± 26.7	0.113
−	502.7 ± 341.9		44.2 ± 32.3
Carcinoembryonic antigen
<5 ng/ml	464.0 ± 322.3	0.501	37.7 ± 32.0	0.326
≥5 ng/ml	512.6 ± 331.3		35.1 ± 26.9
Number of metastases
1	469.1 ± 353.4	0.537	46.7 ± 32.4	0.012
2	459.0 ± 262.1		27.6 ± 26.5
≥3	553.0 ± 335.4		22.6 ± 21.0