Table 2.
Genotypes of 66 Clinical CRKP Strains
| N | Carbapenemase | ESBLs | AmpC | Int | Virulence Gene | Gene Cassette | ISCR | MLST | Replicon Type |
|---|---|---|---|---|---|---|---|---|---|
| 16 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST11 | IncFII |
| 26 | NDM-1 | SHV+CTX-M | DHA | entB+mrkD | ISCR I | ST4495 | lncX3 | ||
| 27 | NDM-1 | SHV+CTX-M | DHA | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 30 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST11 | IncFII |
| 32 | NDM-1 | SHV+CTX-M | DHA | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 34 | NDM-1 | SHV+CTX-M | DHA | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 36 | NDM-1 | SHV+CTX-M | DHA | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 37 | NDM-1 | SHV+CTX-M | DHA | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 39 | NDM-1 | SHV | DHA | entB+mrkD | ISCR I | ST4495 | lncX3 | ||
| 40 | NDM-1 | SHV | DHA+ACC | entB+fimH | ISCR I | ST37 | lncX3 | ||
| 45 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | ||
| 46 | NDM-1 | SHV+CTX-M | DHA+ACC | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 49 | NDM-1 | SHV+CTX-M | DHA+ACC | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 51 | KPC-2 | SHV+CTX-M | ACC | entB+fimH+mrkD | ST11 | ||||
| 56 | NDM-1 | SHV+CTX-M | DHA+ACC | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 57 | NDM-1 | SHV+CTX-M | DHA+ACC | entB+fimH+mrkD | ISCR I | ST4495 | lncX3 | ||
| 58 | NDM-1+IMP-4 | SHV+CTX-M | DHA+ACC | entB+fimH | ST4495 | lncX3 | |||
| 101 | NDM-1 | SHV | ACC | entB+fimH+mrkD | ST37 | lncX3 | |||
| 131 | KPC-2 | SHV+TEM | ACC | IntI | entB+fimH+mrkD+rmpA/rmpA2+iucA+terB+aerobactin+HI1B+iroN+iutA | addA2 | ISCR I | ST11 | IncFII |
| 210 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 211 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 214 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 215 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 221 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST11 | IncFII |
| 223 | KPC-2 | SHV+TEM+CTX-M | ACC | entB+fimH+mrkD | ST147 | ||||
| 227 | KPC-2 | SHV+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 228 | KPC-2 | SHV+CTX-M | ACC | entB+fimH+mrkD | ST11 | IncFII | |||
| 230 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 232 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 233 | KPC-2 | SHV | ACC | IntI | entB+fimH+mrkD | dfrA12, addA2 | ST147 | IncFII | |
| 234 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | InFIB | |
| 241 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 244 | KPC-2 | SHV | ACC | IntI | entB+fimH+mrkD | dfrA12 | ST23 | IncFII | |
| 245 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 251 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 252 | KPC-2 | SHV+TEM+CTX-M | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | ||
| 257 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | ||
| 258 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 267 | NDM-1 | SHV | ACC | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST11 | lncX3 |
| 271 | KPC-2 | SHV+TEM+CTX-M | ACC | entB+fimH+mrkD | ST11 | IncFII | |||
| 285 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 354 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 406 | KPC-2 | SHV+TEM | DHA | IntI | fimH+mrkD | OXA-10, addA1, aacA4 | ISCR I | ST318 | IncFII |
| 436 | KPC-2 | SHV+TEM | DHA | IntI | entB+fimH+mrkD | addA2 | ST17 | IncFII | |
| 440 | NDM-1 | SHV+TEM | ACC | IntI | mrkD | addA2 | ST307 | lncX3 | |
| 445 | NDM-1 | SHV+TEM | ACC | mrkD | ST307 | lncX3 | |||
| 473 | NDM-1+IMP-4 | SHV+TEM | ACC | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST152 | lncX3 |
| 475 | NDM-1 | SHV+TEM | ACC | IntI | fimH+mrkD | addA2 | ISCR I | ST15 | lncX3 |
| 478 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST11 | IncFII |
| 479 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH | addA2 | ST11 | IncFII | |
| 480 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 483 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 489 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | dfrA12, addA2 | ST11 | ||
| 490 | KPC-2 | SHV | ACC | IntI | entB+fimH+mrkD | dfrA27, arr3 | ST467 | IncFII | |
| 494 | NDM-5 | SHV+CTX-M | DHA | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST2407 | lncX3 |
| 495 | KPC-2 | SHV+TEM+CTX-M | IntI | entB+fimH+mrkD | dfrA12 | ISCR I | ST11 | IncFII | |
| 496 | KPC-2 | SHV+TEM | ACC | IntI | entB+fimH+mrkD | gcuF, dfrA12 | ST405 | ||
| 497 | KPC-2 | SHV+TEM | IntI | entB+fimH+mrkD+rmpA/rmpA2+iucA+ terB+wcaG+ aerobactin+HI1B+iroN+iutA | addA2 | ST11 | IncFII | ||
| 498 | KPC-2 | SHV+CTX-M | ACC | IntI | entB+mrkD | dfrA12 | ST11 | IncFII | |
| 499 | NDM-5 | SHV+CTX-M | DHA | IntI | entB+fimH+mrkD | addA2 | ISCR I | ST2407 | lncX3 |
| 500 | KPC-2 | SHV+TEM+CTX-M | ACC | entB+fimH+mrkD | ST11 | ||||
| 502 | NDM-5 | SHV+CTX-M | DHA | IntI | entB+fimH+mrkD | addA2 | ST2407 | lncX3 | |
| 504 | NDM-5+IMP-4 | SHV+TEM+CTX-M | DHA | IntI | entB+fimH+mrkD | addA2 | ST11 | lncX3 | |
| 505 | KPC-2 | SHV+TEM+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII | |
| 506 | NDM-1 | SHV+CTX-M | DHA | IntI | entB+fimH+mrkD | addA2 | ST4495 | lncX3 | |
| 507 | KPC-2 | SHV+CTX-M | ACC | IntI | entB+fimH+mrkD | addA2 | ST11 | IncFII |
Abbreviations: ESBL, extended-spectrum β-lactamase; Int, integron; ISCR, insertion sequence common region.