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. 2021 Aug 13;14:3145–3158. doi: 10.2147/IDR.S324244

Table 3.

Clinical Characteristics of CRKP and CSKP Strains

Variable CRKP (n=66) CSKP (n=66) P-value
Demographic, n (%) or IQR
Age (years) 44.5 (0,60) 46.5 (0.61) 0.754
Sex (male) 47 (71.2%) 46 (69.7%) 0.894
Length of hospital stays 15 (7, 27) 25 (10, 38) 0.1
Admission to ICU 14 (21.1%) 7 (10.6%) 0.096
Co-morbidity, n (%)
Malignant disease 7 (10.6%) 15 (22.7%) 0.062
Diabetes mellitus 11 (16.7%) 12 (18.2%) 0.819
Hypertension 16 (24.2%) 16 (24.2%) 1
Heart disease 9 (13.6%) 11 (16.7%) 0.627
Hepatobiliary disease 12 (18.2%) 15 (22.7%) 0.517
Respiratory disease 45 (68.2%) 33 (50%) 0.034
Renal disease 7 (10.6%) 16 (24.2%) 0.039
Urinary tract infection 10 (15.2%) 9 (13.6%) 0.804
Craniocerebral disease 15 (22.7%) 9 (13.6%) 0.176
Hematological disease 32 (48.5%) 19 (28.8%) 0.02
Gastrointestinal disease 8 (12.1%) 5 (7.6%) 0.381
Invasive procedures and devices
Tracheal cannula 24 (36.4%) 7 (10.6%) <0.001
Central venous catheter 5 (7.6%) 12 (18.2%) 0.069
Foreign material in the body 14 (21.2%) 7 (10.6%) 0.096
Surgical operations after admission 9 (13.6%) 16 (24.2%) 0.12
Colostomy 3 (4.5%) 1 (1.5%) 0.612
Gastrostomy 2 (3%) 0 0.476
Antibiotic treatment, n (%)
Penicillins 2 (3%) 5 (7.6%) 0.437
First, second-generation cephalosporins 7 (10.6%) 15 (22.7%) 0.21
Third, fourth-generation cephalosporins 17 (25.8%) 19 (28.8%) 0.696
Aminoglycosides 4 (6.1%) 1 (1.5%) 0.362
Quinolones 20 (30.3%) 21 (31.8%) 0.851
Metronidazole 0 1 (1.5%) 1
Carbapenems 30 (45.5%) 32 (48.5%) 0.727
β-lactams and β-lactamase inhibitor combination 40 (60.6%) 25 (37.9%) 0.009
Clinical outcomes, n (%)
Patient outcome: mortality 5 (7.6%) 0 0.068

Note: Bold indicates P < 0.05.

Abbreviations: IQR, interquartile range; CR, carbapenem-resistant; CS, carbapenem-susceptible; ICU, intensive care unit.