Table 3.
Variable | CRKP (n=66) | CSKP (n=66) | P-value |
---|---|---|---|
Demographic, n (%) or IQR | |||
Age (years) | 44.5 (0,60) | 46.5 (0.61) | 0.754 |
Sex (male) | 47 (71.2%) | 46 (69.7%) | 0.894 |
Length of hospital stays | 15 (7, 27) | 25 (10, 38) | 0.1 |
Admission to ICU | 14 (21.1%) | 7 (10.6%) | 0.096 |
Co-morbidity, n (%) | |||
Malignant disease | 7 (10.6%) | 15 (22.7%) | 0.062 |
Diabetes mellitus | 11 (16.7%) | 12 (18.2%) | 0.819 |
Hypertension | 16 (24.2%) | 16 (24.2%) | 1 |
Heart disease | 9 (13.6%) | 11 (16.7%) | 0.627 |
Hepatobiliary disease | 12 (18.2%) | 15 (22.7%) | 0.517 |
Respiratory disease | 45 (68.2%) | 33 (50%) | 0.034 |
Renal disease | 7 (10.6%) | 16 (24.2%) | 0.039 |
Urinary tract infection | 10 (15.2%) | 9 (13.6%) | 0.804 |
Craniocerebral disease | 15 (22.7%) | 9 (13.6%) | 0.176 |
Hematological disease | 32 (48.5%) | 19 (28.8%) | 0.02 |
Gastrointestinal disease | 8 (12.1%) | 5 (7.6%) | 0.381 |
Invasive procedures and devices | |||
Tracheal cannula | 24 (36.4%) | 7 (10.6%) | <0.001 |
Central venous catheter | 5 (7.6%) | 12 (18.2%) | 0.069 |
Foreign material in the body | 14 (21.2%) | 7 (10.6%) | 0.096 |
Surgical operations after admission | 9 (13.6%) | 16 (24.2%) | 0.12 |
Colostomy | 3 (4.5%) | 1 (1.5%) | 0.612 |
Gastrostomy | 2 (3%) | 0 | 0.476 |
Antibiotic treatment, n (%) | |||
Penicillins | 2 (3%) | 5 (7.6%) | 0.437 |
First, second-generation cephalosporins | 7 (10.6%) | 15 (22.7%) | 0.21 |
Third, fourth-generation cephalosporins | 17 (25.8%) | 19 (28.8%) | 0.696 |
Aminoglycosides | 4 (6.1%) | 1 (1.5%) | 0.362 |
Quinolones | 20 (30.3%) | 21 (31.8%) | 0.851 |
Metronidazole | 0 | 1 (1.5%) | 1 |
Carbapenems | 30 (45.5%) | 32 (48.5%) | 0.727 |
β-lactams and β-lactamase inhibitor combination | 40 (60.6%) | 25 (37.9%) | 0.009 |
Clinical outcomes, n (%) | |||
Patient outcome: mortality | 5 (7.6%) | 0 | 0.068 |
Note: Bold indicates P < 0.05.
Abbreviations: IQR, interquartile range; CR, carbapenem-resistant; CS, carbapenem-susceptible; ICU, intensive care unit.