Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep;27(9):1004–1016. doi: 10.1261/rna.078709.121

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Johnson et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article, published in RNA, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

FIGURE 3. — Consistent variation for AGO2 protein binding cluster's gene expression changes in TNRC6 and AGO knockout cells. (A) Venn diagram showing the overlap of gene expression changes associated with AGO2 binding within 3′-UTRs. AGO2 binding was determined by eCLIP as described (Chu et al. 2020) and was required for inclusion. (B) Heatmap showing gene expression changes (Log₂FoldChange) shared by TNRC6 and AGO knockout cell lines. (C) Correlation plot of the 67 overlapping genes shown in B of AGO 123^−/− and TNRC6 AB^−/− siC log₂FoldChanges. Shaded region is 95% confidence band.