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a The protein level of E-cad, ZO-1, vimentin, MMP9, and pERK in GFP, GINS2-GFP, and GINS2-GFP combining PD98059 groups. b The quantification of WB data (a). c GINS2 was co-immunoprecipitated with ERK in Miapaca-2 and PANC-1 cells. d GINS2 was colocalized with ERK in Miapaca-2 and PANC-1 cells by IF. 1: GFP, 2: GINS2-GFP, 3: GINS2-GFP plus PD98059. Bars indicate ± SE. *P < 0.05; **P < 0.01 in contrast with the control.
