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. 2021 Aug 3;9:707143. doi: 10.3389/fcell.2021.707143

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Copyright © 2021 Liu, Shang, Li and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The Cox regression analysis and function enrichment analysis. (A) The univariate Cox regression (green) and (B) multivariate Cox regression (red) analysis of six types of TIICs in LUAD and LUSC. The vertical dashed line represents HR = 1. B cell was a protective factor for LUAD (HR < 1), whereas DC1 was a harmful factor of LUSC (HR > 1). (C) GO and (D) KEGG enrichment analysis of 29 genes strongly related to B cell in TCGA-LUAD and 487 genes highly related to DC1 in TCGA-LUSC, respectively. The horizontal axis, gene ratio, represents the proportion of highly related genes contained in the corresponding term to the total highly related genes. The size of the dot indicates the number of highly related genes contained in the corresponding term.