Table 1.
Baseline and clinical characteristics of study participants.
| Variables | Healthy controls (n = 56) | BA patients (n = 96) | P-value |
|---|---|---|---|
| Age (years) | 8.92 ± 0.47 | 10.00 ± 6.17 | 0.59 |
| Gender (male: female) | 32:24 | 50:46 | 0.55 |
| BMI (kg/m2) | 15.78 ± 2.19 | 17.23 ± 3.07 | 0.53 |
| Liver stiffness (kPa) | 4.05 ± 0.11 | 31.02 ± 2.38 | < 0.001* |
| AST (IU/L) | 27.12 ± 0.89 | 133.72 ± 9.90 | < 0.001* |
| ALT (IU/L) | 9.16 ± 0.75 | 127.04 ± 9.12 | < 0.001* |
| ALP (IU/L) | – | 425.85 ± 34.05 | NA |
| Albumin (g/dL) | – | 4.07 ± 0.84 | NA |
| TB (mg/dL) | – | 2.01 ± 1.41 | NA |
| DB (mg/dL) | – | 1.70 ± 1.32 | NA |
ALP alkaline phosphatase, ALT alanine aminotransferase, APRI AST to platelet ratio index, AST aspartate aminotransferase, BA biliary atresia, BMI body mass index, DB direct bilirubin, TB total bilirubin, NA not available.
*Difference is considered statistically significant at P-value less than 0.05 (two-tailed).