Table 2.
Parasitemia level and leukocyte differential counts in co-infections and Plasmodium mono-infections.
| No. | Author, year | Parasitemia level (cells/µL) | Leukocyte counts (103 cells/µL) | Neutrophil counts (103 cells/µL) | Lymphocyte counts (103 cells/µL) | ||||
|---|---|---|---|---|---|---|---|---|---|
| Co-infection | Plasmodium mono-infection | Co-infection | Plasmodium mono-infection | Co-infection | Plasmodium mono-infection | Co-infection | Plasmodium mono-infection | ||
| 1. | Addissie et al. (2007)21 | NA | NA | NA | NA | NA | NA | NA | NA |
| 2. | Amodu-Sanni et al. (2020)22 | NA | NA | NA | NA | NA | NA | NA | NA |
| 3. | Berg et al. (2014)2 | NA | NA | NA | NA | NA | NA | NA | NA |
| 4. | Berg et al. (2008)23 | NA | NA | NA | NA | NA | NA | NA | NA |
| 5. | Berg et al. (2020)24 | NA | NA | NA | NA | NA | NA | NA | NA |
| 6. | Berkley et al. (2009)25 | 37,500 (2680–172,150) (n = 133) | 22,352 (2213–142,590) (n = 938) | NA | NA | NA | NA | NA | NA |
| 7. | Beyene et al. (2017)26 | NA | NA | NA | NA | NA | NA | NA | NA |
| 8. | Bronzan et al. (2007)27 | 52,048 (n = 178) | 40,356 (n = 941) | 10.5 | 11.4 | NA | NA | NA | NA |
| 9. | Chalwe et al. (2009)28 | 43,314 (25,467–81,145) (n = 27) | 11,745 and 38,942 (n = 2) | 6.9 (3.9) | 4.2 and 8.7 | NA | NA | 1.73 (0.43) | 1.16 (0.58) |
| 10. | Cohen et al. (2005)15 | NA | NA | NA | NA | NA | NA | NA | NA |
| 11. | Davenport et al. (2010)29 | 16,220 (43,127) (n = 24) | 22,281 (51,064) (n = 406) | 13.3 (8.4) | 11.2 (6.6) | 35.6 (21.1) | 41.0 (22.8) | 49.4 (16.7) | 50.0 (19.2) |
| 12. | Grimwade et al. (2004)42 | NA | NA | NA | NA | NA | NA | NA | NA |
| 13. | Hendriksen et al. (2012)30 |
Aged < 15: 47,141 (38,005–58,474) (n = 74) Aged ≥ 15: 133,653 (59,082–302,343) (n = 581) |
Aged < 15: 68,320 (37,680–123,874) (n = 49) Aged ≥ 15: 61,525 (24,628–153,704) (n = 19) |
NA | NA | NA | NA | NA | NA |
| 14. | Hochman et al. (2015)31 |
CM1: 98,300 (48,200–324,800) (n = 7) CM2: 56,400 (28,800–308,700) (n = 7) |
CM1: 49,200 (5,100–717,600) (n = 5) CM2: 13,200 (7,500–433,300) (n = 33) |
CM1: 14.5 (12.1–17.1) CM2: 13.2 (10.9–19.3) |
CM1: 11.2 (7.3–15.7) CM2: 12.4 (9.1–21.5) |
NA | NA |
CM1: 2.4 (1.5, 5.1) CM2: 2.7 (1.5–5.3) |
CM1: 2.3 (2–5.5) CM2: 5.3 (2.2–7.8) |
| 15. | Huson et al. (2015)32 | 54,000 (17,340–134,700) (n = 14) |
4,740 (1,300– 18,300) (n = 113) |
5.1 (3.3–6.6) | 5.3 (3.9–7.2) | NA | NA | NA | NA |
| 16. | Imani et al. (2011)43 |
Cerebral malaria 240,000 (3080–583,520) (n = 9) |
Cerebral malaria 21,440 (1600–133,080) (n = 91) |
NA | NA | NA | NA | NA | NA |
| 17. | Jacques et al. (2019)33 | NA | NA | NA | NA | NA | NA | NA | NA |
| 18. | Joice et al. (2016)34 | 20,200 (2900–32,500) (n = 20) | 7400 (800–42,400) (n = 75) | 13.6 (11.9–14.7) | 11.2 (8.8–18.4) | NA | NA | NA | NA |
| 19. | Kyeyune et al. (2014)44 | NA | NA | NA | NA | NA | NA | NA | NA |
| 20. | Mandala et al. (2018)35 | NA | NA | 10.20 (7.85–13.75) (n = 9) | 11.20 (7.90–15.30) (n = 29) | 6.30 (5.23–12.35) | 7.40 (4.6–12.50) | 1.10 (0.85–1.73) | 2.01 (1.50–3.2) |
| 21. | Mouala et al. (2008)36 | NA | NA | NA | NA | NA | NA | NA | NA |
| 22. | Munyenyembe et al. (2018)37 | NA | NA | Severe malaria 6.15 (2.9–14.2) (n = 12), uncomplicated malaria 4.3 (2.4–9) (n = 18) | Severe malaria 5 (2.4–7.25) (18), uncomplicated malaria 5.6 (3.9–10.5) (n = 58) | Severe malaria 3.46 (0.9–12.4), uncomplicated malaria 2.25 (2.1–4.1) | Severe malaria 2.72 (1.1–3.74), uncomplicated malaria 3.03 (1.7–7.7) | Severe malaria 2.25 (1.1–2.8), uncomplicated malaria 1.4 (0.62–3.15) | Severe malaria 1.26 (0.6–3.3), uncomplicated malaria 1.58 (0.74–3.04) |
| 23. | Niyongabo et al. (1994)45 | NA | NA | NA | NA | NA | NA | NA | NA |
| 24. | Nkuo-Akenji et al. (2008)38 | NA | NA | NA | NA | NA | NA | NA | NA |
| 25. | Otieno et al. (2006)46 | NA | NA | NA | NA | NA | NA | NA | NA |
| 26. | Sandie et al. (2019)39 | NA | NA | NA | NA | NA | NA | NA | NA |
| 27. | Saracino et al. (2012)40 | 1.8 ± 1.1 (n = 51) | 2.3 ± 1.2 (n = 39) | 7.7 ± 2.5 | 7.7 ± 3.7 | NA | NA | NA | NA |
| 28. | Tagoe DNA and Boachie (2012)41 | NA | NA | NA | NA | NA | NA | NA | NA |
| 29. | Tay et al. (2015)17 | NA | NA | NA | NA | NA | NA | NA | NA |
NA not applicable.