Table 1.
List of existing normalisation methods.
| Tags | Method | Resource/implementation |
|---|---|---|
| log2Raw_batch | RUV-III21 | R package ruv version 0.9.7.1 |
| MetNormalizer+SVR | Support vector regression | R package MetNormalizer5 version 1.3.02 |
| NormalizeMets+RLSC | Robust locally estimated scatterplot smoothing44 | R package NormalyzeMets11 version 0.24 |
| SERRF | Systematic error removal using random forest15 | Online: https://slfan.shinyapps.io/ShinySERRF/ |
| NormalyzerDE_RLR | Global robust linear regression12 | R package NormalyserDE8 version 1.7.0 |
| NormalyzerDE_CycLoess | Cyclic loess45 | |
| NormalyzerDE_VSN | Variance-stabilising normalisation46 | |
| NormalyzerDE+GI | Global intensity | |
| NormalyzerDE+Quantile | Quantile normalisation47 | |
| NormalyzerDE+mean | Mean48 | |
| NormalyzerDE+median | Median49 | |
| NormalyzerDE+log2 | log2 transformation | |
| Ratio | Ratio50 |