Table 4.
Comparison of CSA results for brain and SC MRI differentiated by center.
| Cord level | C1–C2 | C2/C3 | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Software method | SCT | NQL | ASM | SCT | NQL | ASM | |||||||||||||||
| Site Nr. | Ven-dor | Magnet-length (cm) | N | CSA (mm 2 , mean) | Diff. | CSA (mm 2 , mean) | Diff. | CSA (mm 2 , mean) | Diff. | CSA (mm 2 , mean) | Diff. | CSA (mm 2 , mean) | Diff. | CSA (mm 2 , mean) | Diff. | ||||||
| Brain | Cord | Brain | Cord | Brain | Cord | Brain | Cord | Brain | Cord | Brain | Cord | ||||||||||
| 1 | PHI | 157 | 3 | 65.9 | 69.0 | −3.1 | 74.8 | 75.4 | −0.6 | 74.9 | 75.1 | −0.2 | 66.0 | 68.8 | −2.8 | 69.3 | 69.9 | −0.6 | 73.3 | 73.1 | 0.2 |
| 2 | PHI | 157 | 3 | 65.5 | 68.8 | −3.3 | 73.8 | 75.1 | −1.3 | 73.8 | 75.5 | −1.7 | 67.3 | 68.2 | −0.9 | 67.3 | 68.6 | −1.3 | 71.9 | 73.2 | −1.3 |
| 3 | SIE | 198 | 3 | 65.0 | 67.8 | −2.8 | 73.2 | 75.1 | −1.9 | 73.6 | 75.8 | −2.2 | 64.9 | 68.7 | −3.8 | 65.8 | 68.8 | −3 | 69.6 | 74.3 | −4.7 |
| 4 | PHI | 157 | 3 | 64.1 | 68.5 | −4.4 | 73.4 | 74.8 | −1.4 | 73.5 | 76.4 | −2.9 | 66.2 | 67.9 | −1.7 | 66.1 | 69.6 | −3.5 | 71.5 | 74.2 | −2.7 |
| 5 | GE | 194 | 3 | 66.1 | 65.9 | 0.2 | 75.3 | 75.7 | −0.4 | 75.3 | 75.6 | −0.3 | 65.8 | 63.7 | 2.1 | 68.8 | 69.9 | −1.1 | 72.8 | 71.4 | 1.4 |
| 6 | SIE | 198 | 3 | 68.7 | 67.0 | 1.7 | 76.4 | 76.0 | 0.4 | 76.9 | 77.3 | −0.4 | 69.5 | 67.0 | 2.5 | 69.7 | 69.9 | −0.2 | 73.5 | 74.5 | −1 |
| All sites | 18 | 65.9 | 67.8 | −2.0* | 74.5 | 75.4 | −0.9* | 74.7 | 76.0 | −1.3* | 66.7 | 67.4 | −0.8 | 67.8 | 69.4 | −1.6* | 72.1 | 73.5 | −1.4* | ||
PHI, Philips; SIE, Siemens; GE, General Electric; SCT, Spinal Cord Toolbox; NQL, NeuroQLab; ASM, Active Surface Method; CSA, cross-sectional area; Diff, difference between mean of brain and cord MRI results [mm2].
Marked bold: results of CSA pooled across all sites;
*
p < 0.050 using paired Kruskal–Wallis test.
Site Numbers: 1 = Ospedale San Raffaele, Milano; 2 = Ruhr-University of Bochum, Bochum; 3 = Hospital Universitari Vall d'Hebron, Barcelona; 4 = University College London, London; 5 = VU University Medical Center, Amsterdam; 6 = Basel University Hospital Basel, Basel.