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Survival analysis and weight of Glb1G455R mice. (a) Schematic showing the generation of the Glb1 p.G455R knock-in mouse model. (b) Confirmation of the Glb1 p.G455R mutation by genomic DNA sequencing. (c) Decreased survival of KI/KI mice. For survival analysis n = 7 per group. (d) Serial body weights in female and male mice of the indicated genotype are shown as mean ± SEM. n for 4–13 mice per genotype. (A color version of this figure is available in the online journal.)
