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Numerous autolysosomes that were observed by electron microscopy in KI/KI mice. Electron microscopy images of cerebral cortex from 16-week-old KI/KI mice, wild type (WT), and KI/+ mice: objective ×2.5k; scale bar indicates 5 μm. Spinal cord control: objective ×8k; scale bar indicates 1 μm. Cell nuclei marked as N, autolysosomes marked as AL, lysosomes marked as Ly, cristae marked as M, and rough endoplasmic reticulum marked as RER.
