Table 2.
Male |
Female |
|||||
---|---|---|---|---|---|---|
Latency to fall (s) | Glb1 +/+ | Glb1 G455R/+ | Glb1 G455R/G455R | Glb1 +/+ | Glb1 G455R/+ | Glb1 G455R/G455R |
Forelimb grip strength test | ||||||
8 weeks | 347.2 ± 90.2 | 357.3 ± 91.9 | 72.9 ± 25.3 | 512.6 ± 58.7 | 465.4 ± 73.0 | 105.7 ± 31.7 |
16 weeks | 129.5 ± 52.7 | 49.5 ± 25.0 | 10.6 ± 2.5 | 413.0 ± 91.5 | 376.9 ± 89.9 | 44.3 ± 35.2 |
32 weeks | 13.5 ± 7.2 | 5.0 ± 1.2 | 3.5 ± 1.2 | 399.8 ± 122.8 | 48.8 ± 23.4 | 3.8 ± 1.0 |
Accelerating rotarod test | ||||||
8 weeks | 140.6 ± 16.6 | 122.0 ± 23.9 | 93.6 ± 28.9 | 163.0 ± 11.6 | 138.3 ± 19.4 | 127.9 ± 20.1 |
16 weeks | 159.3 ± 10.8 | 156.3 ± 14.1 | 98.1 ± 19.0 | 138.1 ± 15.0 | 137.5 ± 14.3 | 75.5 ± 9.2 |
32 weeks | 108.6 ± 15.8 | 92.3 ± 7.9 | 22.5 ± 4.3 | 117.2 ± 14.7 | 76.8 ± 15.3 | 64.8 ± 15.2 |
Note: Data represent mean ± SEM.