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. 2021 Aug 4;12:726141. doi: 10.3389/fphar.2021.726141

TABLE 3.

RoB2 assessment for included studies.

Domain Description Study 1 Study 2 Study 3
Matzneller et al NCT01048866 NCT01049334
1 Risk of bias arising from the randomisation process Low risk Low risk Low risk
2 Risk of bias due to deviations from the intended interventions (effect of assignment to intervention) Low risk Low risk Low risk
3 Missing outcome data Low risk Low risk Low risk
4 Risk of bias in measurement of outcome Low risk Low risk Low risk
5 Risk of bias in the selection of the reported result Some concerns Some concerns Some concerns
Overall risk of bias Some concerns Some concerns Some concerns