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LLPS system and molecules used in this study. (A) Schematic illustration of droplet formation in ssDNA/H1 mixtures via LLPS. (B) Structural drawing of histone H1 with lysine-rich IDRs at the N- and C-terminus. The IDRs were estimated using three different structure-prediction algorithms (for details, see the Supplementary Figure 1). (C) Chemical structures of the ssDNA-based oligomers.
