Table 2.
Hazard ratios and 95%CIs of the cardiovascular disease and all-cause mortality in MetS-developed and MetS-recovery groups according to the age of MetS status change.
| Outcomes | Hazard ratio (95% CI) † | Pinteraction | ||
|---|---|---|---|---|
| All age | <50 years | ≥50 years | ||
| MetS-developed vs. MetS-free | ||||
| Cardiovascular disease | ||||
| MetS-free | 1 (reference) | 1 (reference) | 1 (reference) | 0.003 |
| MetS-developed | 1.78 (1.51–2.11) | 2.20 (1.58–3.05) | 1.64 (1.35–1.99) | |
| All-cause mortality | ||||
| MetS-free | 1 (reference) | 1 (reference) | 1 (reference) | <0.001 |
| MetS-developed | 1.03 (0.87–1.21) | 1.61 (1.13–2.30) | 0.93 (0.77–1.11) | |
| MetS-recovery vs. MetS-stable | ||||
| Cardiovascular disease | ||||
| MetS-stable | 1 (reference) | 1 (reference) | 1 (reference) | 0.005 |
| MetS-recovery | 0.59 (0.48–0.72) | 0.38 (0.24–0.59) | 0.67 (0.54–0.85) | |
| All-cause mortality | ||||
| MetS-stable | 1 (reference) | 1 (reference) | 1 (reference) | 0.030 |
| MetS-recovery | 0.95 (0.80–1.12) | 0.68 (0.43–1.06) | 1.00 (0.84–1.21) | |
Cardiovascular disease was the composite of myocardial infarction, stroke, and heart failure.
†
Hazard ration was adjusted for age, sex, marital status, education level, smoking status, drinking status, physical activity level, salt intake, use of anti-hypertensive drug, anti-diabetic drug, lipid-lowering drug, and family history of myocardial infarction, stroke.
MetS, metabolic syndrome; CI, confidence interval.