Table 1:
Comparison of baseline characteristics of CRIC participants with and without follow-up photography among eligible participants with no prior known cardiovascular disease.
| Has follow-up photograph |
|||||
|---|---|---|---|---|---|
| Total n=1713 | No n=587 (34%) | Yes n=1126 (66%) | p-value* | ||
| Baseline Retinal | No NPR | 1242 (73%) | 407 (69%) | 835 (74%) | 0.009 |
| Level Findings | Mild NPR | 142 (8%) | 46 (8%) | 96 (9%) | |
| NPR | 240 (14%) | 97 (17%) | 143 (13%) | ||
| PR | 89 (5%) | 37 (6%) | 52 (5%) | ||
| Arteriole diameter (^m) | mean (SD) | 149 (14.5) | 149 (15.3) | 149 (14.1) | 0.73 |
| Venule diameter (^m) | mean (SD) | 220 (23.5) | 220 (24.1) | 220 (23.2) | 0.95 |
| eGFR (ml/min/1.73m2) | mean (SD) | 45.4 (18.4) | 41.5 (18.3) | 47.4 (18.0) | <0.001 |
| Urine Protein g/24 hours | <0.10 | 623 (36%) | 183 (31%) | 440 (39%) | <0.001 |
| 0.10 - <0.50 | 482 (28%) | 159 (27%) | 323 (29%) | ||
| 0.50 - <1.50 | 236 (14%) | 86 (15%) | 150 (13%) | ||
| 1.50+ | 183 (11%) | 72 (12%) | 111 (10%) | ||
| Missing | 189 (11%) | 87 (15%) | 102 (9%) | ||
| Age | mean (SD) | 59.7 (10.8) | 60.1 (11.3) | 59.4 (10.6) | 0.21 |
| Race/ethnicity | Hispanic | 80 (5%) | 27 (5%) | 53 (5%) | 0.45 |
| Non-Hispanic Black | 727 (42%) | 263 (45%) | 464 (41%) | ||
| Non-Hispanic White | 824 (48%) | 267 (45%) | 557 (49%) | ||
| Other | 82 (5%) | 30 (5%) | 52 (5%) | ||
| Gender | Women | 777 (45%) | 275 (47%) | 502 (45%) | 0.37 |
| Men | 936 (55%) | 312 (53%) | 624 (55%) | ||
| Diabetes mellitus | Yes | 750 (44%) | 285 (49%) | 465 (41%) | 0.004 |
| Hypertension | Yes | 1503 (88%) | 538 (92%) | 965 (86%) | <0.001 |
| Smoking status | Current smoker | 205 (12%) | 77 (13%) | 128 (11%) | 0.07 |
| Former smoker | 731 (43%) | 261 (44%) | 470 (42%) | ||
| Non-smoker | 777 (45%) | 249 (42%) | 528 (47%) | ||
| Body mass index (kg/m^2) | mean (SD) | 31.5 (7.6) | 31.9 (8.0) | 31.3 (7.4) | 0.12 |
| Normal (<25 kg/m2) | 310 (18%) | 103 (18%) | 207 (18%) | 0.49 | |
| Obese (≥30 kg/m2) | 887 (52%) | 312 (54%) | 575 (51%) | ||
| Overweight (25-<30 kg/m2) | 503 (30%) | 164 (28%) | 339 (30%) | ||
| Systolic BP (mmHg) | mean (SD) | 126.0 (21.2) | 129.3 (22.0) | 124.3 (20.6) | <0.001 |
*
p-values are trend tests for retinal level, smoking, and BMI, chi-square tests for other categorical variables, and t-tests for continuous variables
(N)PR=(Non) Proliferative Retinopathy, eGFR=Estimated Glomerular Filtration Rate, BP=Blood Pressure