Table 1.
Classification of direct-acting antiviral agents[29]
|
Class
|
Drug name
|
HCV genotype
|
| NS3/4A inhibitor | Boceprevir1 | Genotypes 1a and 1b |
| Telaprevir1 | ||
| Simeprevir | ||
| Asunaprevir | ||
| Paritaprevir | ||
| Grazoprevir | ||
| Glecaprevir | ||
| Voxilaprevir | ||
| NS5A inhibitor | Daclatasvir | All HCV genotypes |
| Ledipasvir | ||
| Ombitasvir | ||
| Elbasvir | ||
| Velpatasvir | ||
| Pibrentasvir | ||
| NS5B polymerase inhibitor: Nucleoside analogs | Sofosbuvir | All HCV genotypes |
| NS5B polymerase inhibitor: Non-nucleoside analogs | Dasabuvir | Genotypes 1a and 1b |
1
First generation direct-acting antiviral agents.
HCV: Hepatitis C virus.