Table 3.
The association of the first response evaluation and post-treatment neutrophil-to-lymphocyte ratio according to carbohydrate antigen 19-9 response in carbohydrate antigen 19-9 positive group
|
|
Decline of CA19-9 ≥ 18%
|
Decline of CA19-9 < 18%
|
||||||||
|
Post-treatment NLR
|
< 2.62
|
|
≥ 2.62
|
|
|
< 2.62
|
|
≥ 2.62
|
|
|
|
|
n
= 67
|
%
|
n
= 38
|
%
|
P
value
1
|
n
= 39
|
%
|
n
= 75
|
%
|
P
value
1
|
| 1st Response | 0.002 | 0.009 | ||||||||
| CR/PR | 35 | 52.2 | 10 | 26.3 | 4 | 10.3 | 5 | 6.7 | ||
| SD | 29 | 43.3 | 21 | 55.3 | 21 | 53.8 | 21 | 28.0 | ||
| PD | 3 | 4.5 | 7 | 18.4 | 14 | 35.9 | 49 | 65.3 | ||
1
P value from linear-by-linear association test. NLR: Neutrophil-to-lymphocyte ratio; CA19-9: Carbohydrate antigen 19-9; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease.