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. 2021 Aug 17;4(8):e2121138. doi: 10.1001/jamanetworkopen.2021.21138

Table 4. Factors Associated With Moderate to Severe Vision Impairment (MSVI) and Blindness Stratified by Age and Sex.

Factor Participants with disease-associated MSVI, No. Proportion of participants with disease-associated MSVI, No. (%) (n = 562)a Prevalence of disease-associated MSVI, No. (%) [95% CI] (n = 1149)b Participants with disease-associated blindness, No. Proportion of participants with disease-associated blindness, No. (%) (n = 68)c Prevalence of disease-associated blindness, No. (%) [95% CI] (n = 1149)b
Cataract 324 324 (57.7) 324 (28.2) [25.6-30.8] 33 33 (48.5) 33 (2.9) [1.9-3.8]
Secondary cataract 4 4 (0.7) 4 (0.3) [0-0.7] 0 0 0
Age-related macular degeneration 78 78 (13.9) 78 (6.8) [5.3-8.3] 15 15 (22.1) 15 (1.3) [0.7-2.0]
Myopic maculopathy 13 13 (2.3) 13 (1.1) [0.5-1.7] 3 3 (4.4) 3 (0.3) [0-0.6]
Glaucoma 45 45 (8.0) 45 (3.9) [2.8-5.0] 7 7 (10.3) 7 (0.6) [0.2-1.1]
Nonglaucomatous optic nerve damage 4 4 (0.7) 4 (0.3) [0-0.7] 0 0 0
Macular hole 1 1 (0.2) 1 (0.1) [0-0.3] 0 0 0
Macular edema of unknown origin 2 2 (0.4) 2 (0.2) [0-0.4] 0 0 0
Corneal scar 26 26 (4.6) 26 (2.3) [1.4-3.1] 2 2 (2.9) 2 (0.2) [0-0.4]
Unclear 65 65 (11.6) 65 (5.7) [4.3-7.0] 8 8 (11.8) 8 (0.7) [0.2-1.2]
a

Proportion among all participants with MSVI, which was defined as best-corrected visual acuity worse than 6/18 but equal to or better than 3/60 in the better eye or both eyes (measured by modified Early Treatment of Diabetic Retinopathy Study charts).

b

Prevalence in total study population.

c

Proportion among all participant with blindness, which was defined as best-corrected visual acuity worse than 3/60 in the better eye or both eyes (measured by modified Early Treatment of Diabetic Retinopathy Study charts).