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. 2021 Aug 5;6(3):e26047. doi: 10.2196/26047

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©Daniel S Akerib, Andrew Ames, Martin Breidenbach, Michael Bressack, Pieter A Breur, Eric Charles, David M Gaba, Ryan Herbst, Christina M Ignarra, Steffen Luitz, Eric H Miller, Brian Mong, Tom A Shutt, Matthias Wittgen. Originally published in JMIR Biomedical Engineering (http://biomsedeng.jmir.org), 05.08.2021.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Biomedical Engineering, is properly cited. The complete bibliographic information, a link to the original publication on https://biomedeng.jmir.org/, as well as this copyright and license information must be included.

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Example waveforms. (A) Ventilator connected to the simulator and (B) pressure–volume curve over time for healthy lung model and (C) ventilator connected to the simulator and (D) pressure–volume curve over time for with an acute respiratory distress syndrome 2 lung model. In A and C, flow is shown in blue, pressures are shown in red and green, and volume is shown in gray. ARDS: acute respiratory distress syndrome; I:E: inspiratory-to-expiratory ratio; PEEP: positive end-expiratory pressure; RR: respiratory rate; V: volume.