Figure 2.

PRP-Exos enhance HaCaT cell proliferation and migration. (a) HaCaT cells were able to take up PKH26-labelled PRP-Exos. (b, c) CCK-8 and EdU uptake assays were used to assess the impact of PRP-Exo treatment on HaCaT cells. (d) Flow cytometry was used to assess how PRP-Exos affect cell cycle progression. (e) Western blotting was used to assess levels of cell-cycle associated proteins (cyclin D1 and cyclin D3) following PRP-Exo treatment. (f) Wound healing and (g, h) Transwell assays were used to gauge the impact of PRP-Exos on HaCaT cell migration. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, and ^∗∗∗∗P < 0.0001.