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. 2021 Aug 9;2021:9674809. doi: 10.1155/2021/9674809

Figure 6.

Figure 6

USP15 promotes EIF4A1 deubiquitination to enhance HaCaT cell functionality. (a, b) Western blotting results demonstrating USP15 and EIF4A1 levels in HaCaT cells following siRNA-USP15 treatment. (c) EIF4A1 levels in HaCaT cells following siRNA-USP15 treatment, as assessed via qPCR. (d, e) HaCaT cell proliferation was assessed via CCK-8 and EdU assays following siRNA-EIF4A1 treatment. (f) Western blotting analyses were used to assess EIF4A1 expression HaCaT cells following siRNA-EIF4A1 treatment. (g, h) Wound healing and Transwell assays were used to assess the migratory activity of HaCaT cells following siRNA-EIF4A1 treatment. Data are from three independent experiments. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.