Table 1.
Characteristics of Crohn's disease patients.
| Results (n = 122) | Non-5-ASA (n = 30) | 5-ASA (n = 92) | P value | |
|---|---|---|---|---|
| Age, median (IQR) | 33.0 (26.0–46.0) | 32.5 (20.5–40.3) | 33.5 (28.0–46.0) | 0.082 |
| Age at diagnosis, median (IQR) | 27.0 (21.0–40.0) | 28.0 (16.0–39.0) | 27.0 (22.0–41.8) | 0.184 |
| Female, n (%) | 50 (41.0) | 12 (40.0) | 38 (41.3) | 0.900 |
| Smoking, n (%) | 0.330 | |||
| Never | 95 (77.9) | 25 (83.3) | 70 (76.1) | |
| Former | 2 (1.6) | 1 (3.3) | 1 (1.1) | |
| Current | 25 (20.5) | 4 (13.3) | 21 (22.8) | |
| Age at diagnosis, n (%) | 0.070 | |||
| A1 | 17 (13.9) | 8 (26.7) | 9 (9.8) | |
| A2 | 76 (62.3) | 17 (56.7) | 59 (64.1) | |
| A3 | 29 (23.8) | 5 (16.7) | 24 (26.1) | |
| Location at diagnosis, n (%) | 0.753 | |||
| L1 | 24 (19.7) | 5 (16.7) | 19 (20.7) | |
| L2 | 50 (41.0) | 14 (46.7) | 36 (39.1) | |
| L3 | 48 (39.3) | 11 (36.7) | 37 (40.2) | |
| L4 involvement | 8 (6.6) | 3 (10.0) | 2 (2.2) | 0.095 |
| Behaviour at diagnosis, n (%) | 0.403 | |||
| B1 | 87 (71.3) | 23 (76.7) | 64 (69.6) | |
| B2 | 30 (24.6) | 5 (16.7) | 25 (27.2) | |
| B3 | 5 (4.1) | 2 (6.7) | 3 (3.3) | |
| Perianal disease at diagnosis, n (%) | 5 (4.1) | 1 (3.3) | 4 (4.3) | 1.000 |
| Appendicectomy, n (%) | 31 (25.4) | 8 (26.7) | 23 (25.0) | 0.856 |
| Elevated ESR at diagnosis, n (%) | 73 (59.8) | 19 (63.3) | 54 (58.7) | 0.653 |
| CDAI at diagnosis, median (IQR) | 171.0 (102.0–259.5) | 161.0 (100.0–342.0) | 173.0 (102.0–246.0) | 0.562 |
| Cumulative exposures for treatment, n (%) | ||||
| 5-Aminosalicylic acid | 92 (75.4) | — | — | — |
| Corticosteroid | 68 (55.7) | 15 (50.0) | 53 (57.6) | 0.466 |
| Immunomodulators | 64 (52.5) | 13 (43.3) | 51 (55.4) | 0.249 |
| Biologics | 70 (57.4) | 18 (60.0) | 52 (56.5) | 0.738 |
IQR, interquartile range; ESR, erythrocyte sedimentation rate; CDAI: Crohn's disease activity index; 5-ASA, 5-aminosalicylic acid.