Receiver operating characteristic curve for the Notal OCT Analyzer (NOA): spectral domain OCT (SD-OCT) macular cubes obtained from both the Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany) and Cirrus Zeiss devices (Carl Zeiss Meditech, Dublin, CA). The area under the curve was 0.925. The receiver operating characteristic curve was based on 1051 of the 1127 eyes eligible for the primary analysis. The other 76 eyes were those classified by the NOA as having artefactual retinal fluid actually caused by vitreo-macular interface abnormalities (thus given a negative grade for retinal fluid by the NOA). Because the NOA first allocates a high probability of retinal fluid to these scans but subsequently and automatically grades them as negative, they are excluded from the receiver operating characteristic analysis (but included in all other performance metrics). AUC = area under the curve; ROC = receiver operating characteristic.