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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Radiol Clin North Am. 2021 Sep;59(5):875–886. doi: 10.1016/j.rcl.2021.05.010

Figure 3.

Figure 3.

Colitis in a 53-year-old woman with poorly differentiated adenocarcinoma of the lung treated with durvalumab (anti-PD-L1 therapy). MIP (A), CT (B) and fused FDG PET/CT images (C) acquired 3.5 months after treatment initiation revealed marked FDG uptake in the descending and sigmoid colon (arrowheads) with associated wall thickening and fat stranding consistent with colitis. The patient had bloody diarrhea at the time of the scan; sigmoidoscopy performed a week later showed acute colitis. Symptoms resolved following treatment with prednisone. Follow-up MIP (D), CT (E) and fused FDG PET/CT images (F) obtained 5 months later demonstrated marked improvement.