Table 1.
Studies Assessing Magnesium Levels in Fibromyalgia.
| Investigators | # of fibromyalgia patients | # of controls (matching criteria) | Mg lab measures | Mg levels in fibromyalgia versus controls | Mg levels and fibromyalgia clinical parameters |
|---|---|---|---|---|---|
| Bagis et al24 | 60 (females) | 20 (age, sex, wt.) | Serum | ↓ | Negative correlation |
| Erythrocytes | |||||
| Kasim25 | 25 (females) | 25 (age, sex) | Serum | ↓ | |
| Kim et al26 | 44 (females) | 122 (age, sex, BMI) | Hair | ↓ | |
| Sendur et al27 | 32 (females) | 32 (sex)+age | Serum | ↓ | Negative correlation |
| Andretta et al29 | 53 (females) | 50 (sex)++age, BMI | Serum | No difference | |
| Andretta et al28 | 53 (females) | 50 (sex)++age, BMI | Serum | No difference | No correlation |
| Sakarya et al30 | 40 (females) | 40 (age, sex, geographic location) | Serum | No difference | No correlation |
| Prescott et al31 | 13 | 11 (age, sex) | Plasma | No difference | |
| Red blood cells | |||||
| Bazzichi et al32 | 25 | 25 (age, sex) | Platelets | ↑ | |
| Ng33 | 12 | 12 (age, sex) | Hair | ↑ | |
| Eisinger et al34 | 22 | 23 (age) | Serum | No difference | |
| Erythrocytes | Non-significant ↓ | ||||
| Leukocytes | ↑ | ||||
| Romano and Stiller13 | 100 | 12 | Plasma | No difference | |
| Red blood cells | ↓ |
Abbreviations: Mg, magnesium; wt., weight; BMI, body mass index.
+
Age: no significant difference in age between fibromyalgia patients and controls.
++
Age, BMI: average age and BMI were equivalent in fibromyalgia and control groups.
↓ or↑ , significantly lower or higher Mg levels in fibromyalgia patients compared to controls.
No difference, no difference in Mg levels between fibromyalgia and control groups.
Negative correlation, negative correlation between Mg levels and one or more of the clinical parameters of fibromyalgia.
No correlation, no correlation between Mg levels and one or more of the clinical parameters of fibromyalgia.