| 1 |
Nsp1 |
Nsp1/ribosome 40S interaction interface |
6ZLW
|
NA |
49
|
| 2 |
Phosphatase |
ADP-ribose binding site |
6W02
|
ADP-ribose |
50
|
| 3 |
PLpro (nsp3) |
Active site |
7JIW
|
PLP_Snyder530 |
51
|
| 4 |
Mpro (nsp5) |
Active site |
6W63
|
X77 |
52
|
| 5 |
Mpro (nsp5) |
Dimerization interface |
5RFA
|
Fragment x1187 |
53
|
| 6 |
Primase (nsp7) |
nsp7/nsp8 interaction interface |
6XIP
|
NA |
|
| 7 |
Nsp9 |
Peptide binding site |
6W9Q
|
NA |
54
|
| 8 |
Nsp10 |
Predicted pocket, not annotated |
6ZCT
|
NA |
55
|
| 9 |
RdRp (nsp12) |
NiRAN domain |
6XEZ
|
ADP-Mg2+ |
56
|
| 10 |
RdRp (nsp12) |
Active site |
7BV1
|
NA |
57
|
| 11 |
RdRp (nsp12) |
NTP entry site |
7CTT
|
NA |
57
|
| 12 |
RdRp (nsp12) |
Nsp12-Nsp7/Nsp8 interaction site |
7BV1
|
NA |
58
|
| 13 |
Helicase (nsp13) |
ATP/ADP binding site |
6XEZ
|
NA |
56
|
| 14 |
Helicase (nsp13) |
DNA/RNA binding site |
6ZSL
|
NA |
59
|
| 15 |
Endoribonuclease (nsp15) |
Catalytic site |
6WXC
|
Tipiracil |
60
|
| 16 |
2′-O methyltransferase (nsp16) |
RNA binding site |
6WKS
|
RNA cap |
55,61
|
| 17 |
2′-O methyltransferase (nsp16) |
Active site |
6YZ1
|
Sinefungin |
55
|
| 18 |
2′-O methyltransferase (nsp16) |
Allosteric site |
6WKS
|
Adenosine |
61
|
| 19 |
Spike (post-fusion) |
HR2 linker motif |
6M3W
|
HR2 motif |
62
|
| 20 |
Spike (post-fusion) |
S2 HR1/HR2 bundle fold |
6M3W
|
NA |
62
|
| 21 |
Spike (pre-fusion) |
S2 U-turn loop |
6NB6
|
NA |
62
|
| 22 |
ORF3a |
Predicted pocket, not annotated |
6XDC
|
NA |
63
|
| 23 |
ORF8 |
Predicted pocket, not annotated |
7JTL
|
NA |
64
|
| 24 |
ORF9b |
Lipid binding site |
6Z4U
|
PEG lipid |
65
|
| 25 |
Nucleoprotein |
RNA binding site |
6M3M
|
NA |
66
|
