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. 2021 Aug 4;11:652354. doi: 10.3389/fonc.2021.652354

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Copyright © 2021 Zhang, Yuan, Wang, Xu, Cai, Chen and Ma

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) GSEA software are used to create a heat map of the top 50 genes with high expression levels in the CLM and CRC phenotypes in GSE6988 (the color range is from “red-blue” to show the range of expression values as “high to low”). (B) This figure shows the positive correlation (left) and negative correlation (right) between gene grade and ranking index score. (C–G) GSEA analysis about blood circulation and platelet activation-related gene profiles based on CLM and CRC phenotypes in TCGA database.