Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 10;22(4):724. doi: 10.3892/ol.2021.12985

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — VP suppresses tumor cell migration and invasion as well as tumor growth. (A) Wound healing assay was conducted to detect the effects of VP on Saos-2 cell migration. Magnification, ×100. ***P<0.001 vs. Saos-2. (B) Transwell assays were performed to detect the effects of VP on the invasive ability of Saos-2 cells. Scale bar, 100 µm; magnification, ×100. ***P<0.001 vs. Saos-2. (C) VP inhibited the growth of Saos-2 ×enograft tumors in nude mice compared with that in the untreated group. (D) Changes in the volume and weight of OS xenograft tumors in mice following VP treatment. All experiments were performed in triplicate. ****P<0.0001 vs. OS group. VP, verteporfin; OS, osteosarcoma.