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. 2021 Aug 10;22(4):725. doi: 10.3892/ol.2021.12986

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Diagnosis of early stages (I/II) of gastric cancer. Comparison of circulating biomarker expression between the early stages (I/II) of gastric cancer and NCs. (A) ∆Cq value of miR-130b, (B) NLR, (C) RDW-CV, (G) PDW, (H) M%, (I) R#, (M) Hct, (N) Hb and (O) MLR. Unpaired t-test or Mann-Whitney U test was used to determine statistical significance (*P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001). Area under the curve of the expression of circulating biomarkers for early gastric cancer diagnosis. (D) ∆Cq value of miR-130b, (E) NLR, (F) RDW-CV, (J) PDW, (K) M%, (L) R#, (P) Hct, (Q) Hb and (R) MLR. Hb, hemoglobin; Hct, hematocrit; miR-130b, microRNA-130b; MLR, monocyte to lymphocyte ratio; M%, monocyte percentage; NC, healthy control; NLR, neutrophil to lymphocyte ratio; PDW, platelet distribution width; R#, red blood cell count; RDW-CV, red blood cell distribution width-coefficient of variation.