Table II.
Diagnostic value of different indicators for gastric cancer.
| Variable | AUC (95% CI) | Cut-off index J | Youden | Sensitivity, % | Specificity, % | Accuracy, % | PPV, % | NPV, % | P-value |
|---|---|---|---|---|---|---|---|---|---|
| miR-130b | 0.887 (0.821–0.935) | 0.18 | 0.6222 | 91.11 | 71.11 | 84.44 | 14.00 | 35.99 | 0.001 |
| Hb, g/l | 0.828 (0.753–0.888) | 127.00 | 0.5298 | 68.54 | 84.44 | 73.87 | 8.00 | 39.35 | 0.001 |
| Hct, % | 0.764 (0.682–0.833) | 36.11 | 0.4727 | 53.93 | 93.33 | 67.16 | 4.00 | 43.02 | 0.001 |
| RDW-CV, % | 0.763 (0.681–0.832) | 12.80 | 0.4854 | 68.54 | 80.00 | 72.39 | 10.00 | 37.28 | 0.001 |
| MPV, fl | 0.667 (0.580–0.747) | 9.50 | 0.3227 | 52.27 | 80.00 | 61.65 | 10.00 | 36.85 | 0.001 |
| NLR | 0.757 (0.675–0.827) | 3.13 | 0.4944 | 49.44 | 100.00 | 66.42 | 1.00 | 46.00 | 0.001 |
| MLR | 0.814 (0.738–0.876) | 0.15 | 0.5645 | 80.90 | 75.56 | 79.10 | 11.99 | 36.00 | 0.001 |
| PLR | 0.712 (0.628–0.787) | 188.98 | 0.4507 | 56.18 | 88.89 | 67.16 | 5.99 | 41.02 | 0.001 |
| PDW, % | 0.840 (0.766–0.898) | 15.31 | 0.6823 | 70.45 | 97.78 | 79.70 | 1.99 | 45.69 | 0.001 |
| N% | 0.709 (0.624–0.784) | 70.40 | 0.4494 | 44.94 | 100.00 | 63.43 | 1.00 | 45.91 | 0.001 |
| M% | 0.715 (0.630–0.789) | 4.21 | 0.3860 | 74.16 | 64.44 | 70.90 | 17.00 | 30.25 | 0.001 |
| L% | 0.782 (0.703–0.849) | 25.22 | 0.4844 | 59.55 | 88.89 | 69.40 | 5.99 | 41.11 | 0.001 |
| N#, 109/l | 0.634 (0.547–0.716) | 4.63 | 0.4277 | 49.44 | 93.33 | 64.18 | 4.00 | 42.93 | 0.0044 |
| M#, 109/l | 0.680 (0.594–0.758) | 0.24 | 0.3308 | 77.53 | 55.56 | 70.15 | 20.99 | 26.25 | 0.0004 |
| L#, 109/l | 0.719 (0.635–0.793) | 1.46 | 0.4067 | 60.67 | 80.00 | 67.16 | 10.00 | 37.02 | 0.001 |
Sensitivity, specificity, PPV, NPV, accuracy and Youden index J were calculated based on the numbers of positive and negative cases. AUC, area under the curve; 95% CI, 95% confidence interval; PPV, positive predictive value; NPV, negative predictive value; miR-130b, microRNA-130b; Hb, hemoglobin; Hct, hematocrit; RDW-CV, red blood cell distribution width-coefficient of variation; MPV, mean platelet volume; NLR, neutrophil to lymphocyte ratio; MLR, monocyte to lymphocyte count ratio; PLR, platelet to lymphocyte count ratio; PDW, platelet distribution width; N%, neutrophil percentage; M%, monocyte percentage; L%, lymphocyte percentage; N#, neutrophil count; M#, monocyte count; L#, lymphocyte count.