Table IV.
Accuracy of miR-130b, PDW, MLR and Hb individually and combined for gastric cancer detection.
| Variable | Cut-off | Sensitivity, % | Specificity, % | Accuracy, % | LR+ | LR− | DOR |
|---|---|---|---|---|---|---|---|
| miR-130b | 0.18 | 91.11 | 71.11 | 84.44 | 3.15 | 0.13 | 25.23 |
| PDW,% | 15.31 | 70.45 | 97.78 | 72.39 | 3.43 | 0.39 | 8.71 |
| MLR | 0.15 | 80.90 | 75.56 | 79.11 | 3.31 | 0.25 | 13.09 |
| Hb, g/l | 127.00 | 68.54 | 84.44 | 73.88 | 4.40 | 0.37 | 11.82 |
| miR-130b-PDW | 0.74 | 82.02 | 88.89 | 84.33 | 7.38 | 0.20 | 36.49 |
| miR-130b-MLR | 0.764 | 75.28 | 86.67 | 79.11 | 5.65 | 0.29 | 19.80 |
| miR-130b-Hb | 0.56 | 89.89 | 86.67 | 88.80 | 6.74 | 0.12 | 57.81 |
| PDW-MLR | 0.53 | 71.26 | 97.78 | 80.17 | 32.10 | 0.29 | 109.21 |
| PDW-Hb | 0.50 | 89.66 | 88.89 | 89.40 | 8.07 | 0.12 | 69.38 |
| MLR-Hb | 0.64 | 73.03 | 84.44 | 76.89 | 4.69 | 0.32 | 14.69 |
| miR-130b-PDW-MLR | 0.61 | 94.25 | 91.11 | 93.18 | 10.60 | 0.06 | 167.99 |
| miR-130b-PDW-Hb | 0.77 | 90.80 | 97.78 | 93.18 | 40.90 | 0.09 | 434.71 |
| miR-130b-MLR-Hb | 0.52 | 91.01 | 86.67 | 89.55 | 6.83 | 0.10 | 65.82 |
| PDW-MLR-Hb | 0.55 | 89.66 | 91.11 | 90.15 | 10.09 | 0.11 | 88.87 |
| miR-130b-PDW-MLR-Hb | 0.76 | 91.95 | 97.78 | 93.94 | 41.42 | 0.08 | 503.10 |
LR+, positive likelihood ratio; LR−, negative likelihood ratio; DOR, diagnostic odds ratio; miR-130b, microRNA-130b; PDW, platelet distribution width; MLR, monocyte-lymphocyte count ratio; Hb, hemoglobin.