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. 2021 May 28;118(21):349–356. doi: 10.3238/arztebl.m2021.0127

Table 1. Overview of the most important travel vaccinations.

Vaccination Minimum age Standard vaccination schedule or basic immunization (BI), route of administration Immunity starting from
Hepatitis A 1–18 years, depending on the vaccine 1 × i.m. > 2 weeks after BI
Hepatitis B From birth 0–1–6 months i. m. > 4 weeks after BI
Hepatitis A + B 1–16 years, depending on the vaccine 0–1–6 months i. m. > 2 or 4 weeks after BI
TBE 1–16 years, depending on the vaccine 0–14 days to 9 months (after 2nd vaccine) i. m. 2 weeks after 2nd vaccination for the current season
0–1–5 months (after 2nd vaccine) i. m.
Meningococcal serogroups A, C, W135, Y 6 weeks to 2 years, depending on the vaccine 1 × i.m. > 1 week after BI
Meningococcal serogroup B 2 months or 10 years,depending on the vaccine 0–1 months i.m. or 0–6 months i. m. Immediately after BI (2nd vaccination)
Rabies From birth 0–7–21 (28) days i.m.,rapid schedule *1 : 0–3–7 days i. m. 2–4 weeks after BI
Polio 2 months 0–1–2 months i.m. Immediately after BI (3rd dose)
Yellow fever 9 months 1 × s.c. preferred, see product information for i.m. injection 10 days after BI (consider for entry date)
Japanese encephalitis (JE) 2 months 0–28 days i.m., children < 3 years receive half-doses, rapid schedule*2: 0–7 days i. m. 4 weeks after BI
Typhoid fever 2 years (injectable vaccine) 1 × i.m. 14 days after BI
5 years (oral vaccination) 0–2–4 days, orally; there should be a minimum interval of 3 days between the 3rd vaccination dose and start of malaria prophylaxis > 10 days after BI
Typhus + hepatitis A 16 years 1 × i.m. > 2 weeks after BI
Cholera 2–7 years, depending on the vaccine 1 x or 0–7(–14) days orally, maximum of 6-week interval between doses, otherwise new vaccination 7–10 days after BI, for at least 6 months

Overview of the vaccines most frequently used in Germany for travel medicine. The product information of the respective vaccines should be assessed prior to vaccination. A detailed and continuously updated summary, including rapid vaccination schedules and information on boosters, can be found in tabular form on the website of the authors’ institution (www.uniklinikum-leipzig.de/einrichtungen/medizinische-klinik-2/infektions-und-tropenmedizin); for further details see (22).

*1 Only for adults aged 18–65 years (if the conventional pre-exposure prophylaxis schedule cannot be completed before the required vaccine protection within 21 or 28 days)

*2 Only for adults aged 18–65 years (if the conventional schedule cannot be completed before the required vaccine protection within 28 days)

i.m., intramuscular; s.c., subcutaneous