Skip to main content
. 2021 May 28;118(21):349–356. doi: 10.3238/arztebl.m2021.0127

eTable. Weight-adjusted dosage recommendations on medications for malaria prophlaxis*1 modified from (23).

Body weight (kg) Age Tablets/day Atovaquone/proguanil 62.5/25 mg (junior)*2 Tablets/dayDoxycycline 100 mg*2 Tablets/week Mefloquine 250 mg*2
 5–9 < 4 months ½ (up to 8 kg BW, off-label use) ⅛ tablet
 9–11 4–11 months ¾ (from 8 kg BW, off-label use) ¼ tablet
11–15 1–2 years 1 ¼ tablet
15–19 3–4 years 1 ¼ + ⅛ tablet
19–25 5–7 years 1; or 2 from 21 kg BW ½ tablet
25–36 8–10 years 2; or 3 from 31 kg BW ½ ½–¾ tablet
36–50 11–13 years 3 ‘junior’ tablets; or 1 tablet for adults (250/100 mg) from 40 kg BW ¾ ¾–1 tablet
> 50 > 13 years 1 tablet for adults (250/100 mg) 1 1 tablet

*1 Atovaquone/proguanil (‚junior‘ formulation), doxycycline and mefloquine.

*2 A commercially available pill splitter is recommended for pill splitting. Attention should always be paid to the respective valid product information.