Skip to main content
. 2021 Aug 18;41(33):7003–7014. doi: 10.1523/JNEUROSCI.1964-20.2021

Figure 2.

Figure 2.

sLTP induction disrupts the correlation between PSD and spine head volume. A, B, Serial images of an example spine (A) and 3D reconstruction of the example spine (B), with spine head shown in yellow and PSD shown in red. Scale bar, 200 nm. C, PSD size at early, intermediate, and late phases of sLTP. Welch's t test on log-transformed data. D, Correlation between spine head volume and PSD size for control spines (Ctrl) and sLTP spines at early, intermediate, and late phases of sLTP. Regression line forced through origin. Black line and open circles represent control spines, and red line and solid dots represent sLTP spines at each phase of sLTP. The p value was calculated by comparing the two regression lines with an extra sum-of-squares F test. E, Ratio of PSD area to spine volume at early, intermediate, and late phases of sLTP. Two-way ANOVA followed by Bonferroni's post hoc test was used for comparison between control and sLTP spines, and Tukey's post hoc test was used for comparison among different sLTP phases. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.