Figure 5.

sLTP induces expansion of total ASI postsynaptic membrane. A, B, Serial images of an example spine (A) and 3D reconstruction of the example spine (B) with spine head shown in yellow and ASI shown in green. Scale bar, 200 nm. C, ASI area size at early, intermediate, and late phases of sLTP for sLTP and control (Ctrl) spines. Welch's t test was used on log-transformed data. D, Ratio of ASI area to spine volume at early, intermediate, and late phases of sLTP. Two-way ANOVA followed by Bonferroni's post hoc test was used for comparison between control and sLTP spines, and Tukey's post hoc test was used for comparison among different phases. *p < 0.05, **p < 0.01, ***p < 0.001.