Table 2.
Comparison of the relative changes of dendritic spine ultrastructures in control and sLTP conditions at early, intermediate, and late phases of sLTP
| PSD/spine volumea | ASI/spine volumea | nsASI / spine volumeb | |||
|---|---|---|---|---|---|
| Two-way ANOVA Source of variation |
Interaction |
F(2,224) = 5.261 **p = 0.0059 |
F(2,224) = 7.123 **p = 0.0010 |
F(2,224) = 3.083 *p = 0.0478 |
|
| Phase (early/intermediate/late) |
F(2,224) = 5.579 **p = 0.0043 |
F(2,224) = 7.809 ***p = 0.0005 |
F(2,224) = 5.475 **p = 0.0048 |
||
| Condition (control/LTP) |
F(1,224) = 23.90 ****p < 0.0001 |
F(1,224) = 3.378 p = 0.0674 |
F(1,224) = 0.541 p = 0.4628 |
||
| Tukey's multiple-comparisons test for phases | Control | Early vs intermediate | *p = 0.0449 | p = 0.9829 | p = 0.0525 |
| Early vs late | p = 0.4387 | p = 0.9643 | p = 0.7308 | ||
| Intermediate vs late | p = 0.4027 | p = 0.9986 | p = 0.2324 | ||
| LTP | Early vs intermediate | p = 0.9860 | p = 0.1981 | p = 0.1038 | |
| Early vs late | *p = 0.0108 | ***p = 0.0002 | *p = 0.011 | ||
| Intermediate vs late | *p = 0.0096 | *p = 0.0309 | p = 0.6218 | ||
| Bonferroni's multiple-comparisons test on condition | Early | ****p < 0.0001 | **p = 0.0027 | p = 0.8004 | |
| Intermediate | **p = 0.0036 | p = 0.4996 | p > 0.9999 | ||
| Late | p > 0.9999 | p = 0.2046 | p = 0.0506 | ||
aData consistent with Gaussian distribution, two-way ANOVA performed directly.
bData consistent with log-normal distribution, two-way ANOVA performed on log-transformed data.
*p < 0.05,
**p < 0.01,
***p < 0.001,
****p < 0.0001.