FIGURE 3.

Protscale analysis of wild‐type and mutant CTSC protein. (a) Wild‐type, (b) Mutant. The score of the Cys255Arg site significantly decreased. The tertiary structure of wild‐type CTSC protein (c) and its interaction residues (d). The tertiary structure of mutant‐type CTSC protein (e) and its interaction residues (f). The 255th amino acid is located in a special position, which is near the helix. The 255th residue of wild‐type can interact with residues 252 and 257 in the sequence space respectively. The 255th residue of mutant type can interact with 252, 254, and 328 in the sequence space