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Antigen-specific IgG subtype response at Week 12 elicited in BALB/c mice. Mice (n = 6) were injected with either two intramuscular doses of SARS-CoV-2 S-protein alone or one intramuscular dose of AlPO4- or SQ@NP-adjuvanted SARS-CoV-2 S-protein. Data are presented as GMT with 95% CI of six mice per group. *p < 0.05: Comparison with the group of protein alone. #p < 0.05: Comparison with the AlPO4-adjuvanted protein group.
