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Experimental design of the study. (A) Hierarchical organization of the sampling points. (B) Map of the Nice area, with the indications of the different catchment areas. Haliotis is the name of the central wastewater treatment plant (WWTP). (C) flow-chart of the project, with the different steps of analysis. The ARTIC sequencing protocol is based on a polymerase chain amplification of 2 sets of non-overlapping amplicons that cover the full sequence of the virus.
