Table 1.

Teaching points

1. Vaccines rarely are associated with the development of postvaccination autoimmune phenomena, including de novo ANCA vasculitis.

2. Although the SARS-CoV-2 vaccines are exceptionally safe and effective, de novo ANCA-associated glomerulonephritis can be associated with recent COVID-19 vaccination.

3. ANCA-associated vasculitis should be considered in the differential diagnosis of acute kidney injury following COVID-19 vaccination.

ANCA, antineutrophil cytoplasmic autoantibody; COVID-19, coronavirus disease 2019; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.