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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Histopathology. 2020 Nov 9;78(4):508–519. doi: 10.1111/his.14246

Figure 3. Metastatic chromophobe renal cell carcinoma to the thyroid gland.

Figure 3.

(A) At low power (100X), the tumor is separated from the background thyroid (blue arrow) by a fibrous capsule. (B) At high power (400X), the tumor cells have wrinkled nuclei, binucleation, perinuclear halo, and abundant eosinophilic cytoplasm. (C-F) The tumor shows a PAX8-positive, TTF-1-negative, CK7-positive, and CKIT-negative immunoprofile. Note that the background thyroid is TTF-1 positive (blue arrow in panel D).