Fig 1. The AUC of PRSs derived from the EAS/EUR GWASs alone and meta-analysis of both.
PRSs are derived from EAS, EUR GWASs and fixed effect meta-analysis of the EAS and EUR (denoted as META_FE). PRSs are evaluated in an independent EAS validation dataset for predicting breast cancer risk. Each PRS was plotted against the (A) P-value threshold and (B) number of SNPs included. The corresponding numerical results were reported in S2 Table.