Table 5.
AMH (ng/mL) | No. of cycles | Adjusted Δ in luteal phase length, days (95% CI)b | P value | Adjusted a Δ in luteal phase length, days (95% CI)c | P value | Adjusted a Δ in luteal phase length, days (95% CI)d | P value | |
---|---|---|---|---|---|---|---|---|
<1.6 | 267 | –0.19 (–1.03, 0.63) | .639 | –0.06 (–0.92, 0.80) | .897 | 0.26 (–0.81, 1.33) | .631 | |
1.6-3.4 | 262 | Reference | ||||||
>3.4-8 | 254 | 0.46 (–0.36, 1.29) | .268 | 0.34 (–0.50, 1.18) | .424 | 0.49 (–0.57, 1.56) | .364 | |
>8 | 99 | 1.87 (0.78, 2.95) | .001 | 1.80 (0.71, 2.88) | .001 | 2.04 (0.54, 3.55) | .008 | |
Long luteal phase (≥18 days) | aOR (95% CI) b | aOR (95% CI) c | aOR (95% CI) d | aOR (95% CI) e | ||||
<1.6 | 213 | 0.55 (0.23, 1.28) | — | 0.57 (0.25, 1.31) | — | 0.86 (0.26, 2.82) | — | 0.87 (0.33, 2.28) |
1.6-3.4 | 206 | Reference | ||||||
>3.4-8 | 203 | 1.73 (0.81, 3.71) | — | 1.52 (0.70, 3.32) | — | 3.34 (0.90, 12.46) | — | 1.93 (0.83, 4.51) |
>8 | 82 | 2.89 (1.25, 6.67) | — | 2.86 (1.26, 6.46) | — | 5.08 (1.10, 23.38) | — | 2.66 (1.01, 7.03) |
Results are displayed as change in phase in days for a given AMH category, compared with the reference group.
a To achieve normality of the model residuals, the continuous analysis was limited to phases between 5 and 45 days long.
b Adjusted for age.
c Adjusted for age, race, education, BMI, time since oral contraceptive use, alcohol, smoking, and caffeine consumption.
d Sensitivity analysis of luteal phase length with ovulation determined by OPK (cycle N = 443).
e Sensitivity analysis the association of categorical AMH with long luteal phase weighted by the inverse of cycles contributed by each woman.