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. 2021 Aug 17;11(8):e048436. doi: 10.1136/bmjopen-2020-048436

Table 3.

Age-adjusted incidence rate (per 100 000 person-year) of LLA in people with and without diabetes

Groups Incidence of major LLA
Total 95% CI With diabetes 95% CI Without diabetes 95% CI Relative risk
(With/without)
Men 6.2 5.9 to 6.5 26.4 23.4 to 29.5 2.6 2.3 to 2.8 10.2
Women 3.5 3.3 to 3.7 17.3 14.5 to 20.1 2.0 1.8 to 2.2 8.7
Total 4.8 4.5 to 5.1 21.8 18.9 to 24.7 2.3 2.1 to 2.5 9.5
Groups Incidence of Minor LLA
Total 95% CI With diabetes 95% CI Without diabetes 95% CI Relative risk
(With/without)
Men 7.1 6.7 to 7.5 39.3 35.7 to 43.0 2.2 2.0 to 2.5 17.9
Women 3.0 2.7 to 3.2 18.0 15.4 to 20.5 1.5 1.3 to 1.7 12.0
Total 5.0 4.7 to 5.3 28.4 25.3 to 31.4 1.9 1.7 to 2.1 14.9

LLA, lower limb amputation.